Skill Summary

Experienced in data analyses in linear regression, t-test, ANOVA, survival data, categorical data, logitudial data and mixed-effects models both in basic medical research and in clinical trials, proficient in SAS and R;

Medical data/image acquisition, processing and analysis;

Database/system analysis, design, and maintenance; skilled in MS Windows and Linux; experienced in programming.

Education

MS (candidate), Biostatistics
MS, Information Technology specialized on Internetworking
MS, Information Science
B.Eng., Information Engineering,

Professional Experience

Oct 2007---Present Research Associate, Confidential, Louisville, KY
Core member of Pathology Core serving multi research groups for NIH funded projects, including data collection, processing, graphing, statistic modeling and analyses.

Key Projects & Accomplishments

Data mining for heart disease clinical diagnostic dataset. Conducted independent data mining study, using logistic regression model, generalized linear model, and mixed-effects model for analyses of patient diagnostic dataset, and compared the corresponding results for different models. The poster was accepted by the 12th Annual Data Mining Conference, M2009, Las Vegas.
Clinical trials for lung cancer with bone metastasis. Implemented statistical analyses on different biomarkers for clinical trial phase II study, performed longitudinal data analysis with mixed-effects model, screened the most correlated biomarker. The statistic report was used for supporting paper submission.
Clinical trials for prostate cancer. Performed longitudinal data analysis of treatment cycle effects on PSA marker, conducted survival data analysis on patient survival and time to disease progression, implemented categorical data analysis on the association between the treatment effects and patient pain improvement, and also achieved some complicated plots such as waterfall plot. The statistical report was used for paper submission.
Studies of chronic, long term, different doses of cardiac stem cell treatments, and VSEL stem cell study. Conducted data collection and statistical analyses for basic medical research on morphology and different sets of biomarkers, applied the statistical principles of randomization and blinded for experimental studies, and achieved maximum measure accuracy and precision on data collections. The data and the corresponding statistical analysis reports were used for manuscripts and publications.
Study of CXCR4 antagonism exacerbates myocardial infarction. Conducted data collection and statistical analysis for basic medical research, performed t-test, ANOVA, and non-parametric statistical analyses. The data and statistical analysis resutls were used for paper submission.

Dec 2000 - March 2003 System Analyst/Consultant, Confidential, Stockholm, Sweden
System/database analysis & design, network analysis & design

Key Projects & Accomplishments

Micropayment system analysis and design. Converted business data flow to database concept, performed database concept design, database logical design and physical implementation.
Network analysis and design. Conducted local area network (LAN) design, implementation and test, performed Virtual Private Network (VPN) design, implementation and test for service provider.

Aug 1995---Sep 2000 System engineer, Confidential, Beijing, China
System/database analysis and design on information management system;
Programming in information management system.

Publication (related to data analysis)

Chengxin Li, An Analysis of Cleveland Clinical Heart Disease Diagnostics, Poster, M2009 (12th Annual Data Mining Conference), Las Vegas, 2009.
W. Zhang, G Rabinowits, A. J. Janckila, L. Yam, F. Hendler, D. Laber, C. Li, Goetz H. Kloecker. Effect of zoledronic acid on tartrate resistant acid phosphatase isoform 5b(TRAP-5b) and other bone markers in lung cancer patients with bone metastasis. 01/2010, submitted.
S. Dai, F. Yuan, J. Mu, C. Li, N. Chen, S. Guo, J. Kingery, S. Prabhu, R. Bolli, G. Rokosh. Chronic AMD3100 antagonism of SDF1-CXCR4 Signaling exacerbates cardiac dysfunction and remodeling after myocardial infarction despite increased recruitment of ckitpos, CD34neg, CD45neg progenitors, 01/2010, submitted.
X. Tang, G. Rokosh, S. Sanganalmath, F. Yuan, H. Sato, J. Mu, S. Dai, C. Li, N. Chen, Y. Peng, B. Dawn, G. Hunt, A. Leri, J. Kajstura, S. Tiwari, G. Shirk, P. Anversa, R. Bolli. Intracoronary Administration of Cardiac Progenitor Cells Alleviates Left Ventricular Dysfunction in Rats With a 30-Day-Old Infarction, Circulation. 2009.
X. Tang, G. Rokosh, S. Sanganalmath, Y. Peng, F. Yuan, S. Dai, J. Mu, Q. Bi, C. Li, N. Chen, H. Sato, B. Dawn, P. Anversa, R. Bolli, Beneficial Effects of Cardiac Progenitor Cells on LV Function 1 Year after Treatment in Rats with Myocardial Infarction, Poster, Scientific Sessions 2008, American Heart Association.

Primary Certification

Microsoft Certified Database Administrator (MCDBA).

Reference Available on request.

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Louisville, KY

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