Manager Advanced/Reagents Systems Resume San Francisco - Hire IT People

SUMMARY

Dynamic and Result - oriented Statistical Programmer with extensive experience covering all aspects of R, Python, SQL & SAS processes - including the generation of tables, listings and graphs (TLGs), the creation of analysis datasets, and the design of specifications according to the protocol, SAP and annotated CRF.
Well trained in Good Clinical Practice (GCP), Good Manufacture Practice (GMP), Regulatory Compliance and FDA Guidelines.
Excellent communication, leadership and collaboration skills.
A diligent scientist with more than 9 years of industrial scientific experiences on small molecule anti-HIV drug discovery and immunotherapy cell based bioassay development.
More than 10 years of academic scientific experiences on BLV Molecular Pathology and HIV protein-RNA interaction research.

TECHNICAL SKILLS

Tools: SAS Base, SAS/Stat, SAS/Graph, SQL, Python, R, P21 OpenCDISC

Database: Oracle Clinical, SQL Server 2000, PL/SQL, MS Access

Operating Systems: UNIX WINDOWS MS - DOS

Web Technologies: HTML, JavaScript

Programs: Microsoft Office Suite (Word, Excel, PowerPoint, Access and Outlook)

Molecular Biology: DNA & RNA isolation, PCR, RT-PCR, RT-qPCR, cloning, sequencing, Gene editing

Cell Biology: Cell culture, Transfection, Constructing stable cell lines, Flow Cytometry Gene

Therapeutic: Primary cell isolation & gene editing,Gene array(microarray), ISH, FISH, Drug screening, Viral transductions

Assay Development: Enzyme kinetics, ELISA, Cell viability/Cytotoxicity assay, Cell based bioassay, Biomarker

Bioinformatics: NCBI/BLAST, Sequence alignment, Gene expression (NGS) analysis, RNA-protein interaction, Protein-Protein interaction

PROFESSIONAL EXPERIENCE

Manager Advanced/Reagents Systems

Confidential

Responsibilities:

Solid knowledge and excellent experience in FDA regulations, Data Management and Data Analysis.
Solid knowledge and experience in CDISC to create SDTM and ADaM datasets, and controlled terminologies.
Very good understanding of R&D, clinical study data and hands on experience in data manipulations, analysis and reporting of analysis results.
Designs, develop, evaluate and modify R & SAS programs to analyze and evaluate R&D and clinical data
Meticulously analyzed and validated datasets and outputs using SAS/Base, Stat, ODS, Graph, Macro & SAS/Report. Created formats for the coded data and used SQL for data validation
Work collaboratively with team member in statistical analyses and generating reports
Render support in generating analysis datasets and creating specified structure of TLGs through creating macros and macro variables using advanced SAS & R techniques
Oversee assay development and manufacture of Bioassay Kits and bioassay service for biological samples.
Plan, write, and execute protocol focus to assay development and CRO service.

Data Scientist

Confidential

Responsibilities:

Industry expertise in providing SAS, Python & R Programming and analysis support for oncology drug screen study
Provided operational support by creating tables and graphs to produce manufacture inventory reports using excel and SAS, R program
Develop ELISA assay for oncology pre-clinical trial project(NIH SBIR/STTR grant)

Scientist Advanced Genetic Systems

Confidential, San Francisco

Responsibilities:

Develop cell-based reporter assays to monitor HIV Rev-RRE interactions as high-throughput screen method for identifying specific inhibitors of RNA-protein interactions
Identified small number analogs as anti-HIV compounds (NIH SBIR/STTR grant).