Graduate Research Assistant Resume
Jackson, MS
SUMMARY
High potential Materials Scientist with a multidisciplinary background of clinical experience as a dental surgeon and 3+ years of research experience. Research focus in physico-chemical and mechanical characterization of biomaterials and drug compounds, and expertise in development and testing of polymer-based grafts for tissue engineering and drug delivery applications (patent pending approval). Knowledge and experience in working with standard testing protocols like ISO, ASTM and FDA product approval procedures under GDP/GLP/GMP/GxP environment. Research oriented with effective presentation, oral and written communication skills. Team player with an ability to work well with all levels of an organization. Aspire to contribute and gain more knowledge in the revolutionary field of medical devices with the opportunity for professional growth and career development.
SPECIALITIES
- Laboratory related: Recombinant protein purification, HPLC, MS, infrared spectroscopy (FT-IR), spectrophotometry (UV-Vis), thermal analysis (DSC), mechanical testing (MTS, Instron), polymer degradation studies, scanning electron microscopy (SEM), atomic force microscopy (AFM), confocal microscopy, lyophilization (vacuum freeze-dryer), SDS-PAGE, cell culture and microbiology, fluorescent microscopy, RT-PCR, DNA isolation, histology, staining, immunohistochemistry (ELISA) and histomorphometry
- Software and statistical tools: Microsoft Office, AutoCAD, MathCAD, mathematical modeling, statistical analysis (SPSS), image analysis (Gwyddion, Slidebook, Nanoscope)
- Clinical Procedures: Root Canal Therapy, Aesthetic Restorations, Pedodontic Restorative Procedures, Fixed and Complete Dentures, Extractions, Scaling, Radiology
EXPERIENCE
Graduate Research Assistant 06/2009 – 12/2011
Confidential, Jackson, MS
- Managed the research, development and characterization of novel ELP-collagen composite hydrogel scaffolds for drug delivery and hard tissue augmentation
- Assisted in the ongoing NSF funded project on the formation and characterization of a 3-dimensional aggregate (spheroid) model in primary rat hepatocytes.
- Characterized ELP and collagen polymer hydrogel scaffolds using FTIR, DSC, SEM, AFM, MTS mechanical testing devices
- Investigated the potential of ELP and ELP-collagen composite hydrogels as a carrier for drugs and growth factors and statistical analysis of the release profiles
- Microbiologically tested the efficacy of the released antibiotics against gram negative and gram positive organisms
- Studied the degradation of antibiotic-loaded ELP-collagen scaffolds by utilizing UV-Vis spectrophotometry and SDS-PAGE techniques
- Tested the cell compatibility of ELP-collagen composites by performing several in-vitro biochemical and enzyme-linked assays (DNA, Protein, Live/Dead, ALP and OCN assay)
- Analyzed the mineralization potential of cells cultured on ELP-collagen hydrogel scaffolds by immunohistochemistry and surface staining
Associate Dentist 01/2009-04/2009
Confidential, Mumbai, India
Independent practice at a non-profit charitable organization providing comprehensive dental healthcare services to patients
Assistant Researcher 12/2008-01/2009
Confidential, Mumbai, India
2 months project involving collection of clinical data pertaining to oral manifestations of HIV infection in pediatric patients
EDUCATION
M.S in Biomedical Materials Science
Thesis Title: Elastin-like Polypeptide-Collagen Composite Scaffolds for Drug Delivery and Tissue Engineering
Advisor: Dr. Amol V. Janorkar, Ph.D. Assistant Professor, Department of Biomedical Materials Science
Significant Coursework: Mathematics for Materials Science, Fundamentals of Materials Science, Material Thermodynamics, Fundamentals of Polymer Science, Fundamentals of Biomaterials, Experimental Methods in Materials Science, Biostatistics, Ethical Conduct of Research.
B.D.S (Bachelor of Dental Surgery)
PUBLICATIONS
- Shruti S. Amruthwar, Aaron D. Puckett, and Amol V. Janorkar, Preparation and Characterization of a Novel Biopolymer Composite Hydrogel, Journal of Biomedical Materials Research (submitted), December 2011
- Shruti S. Amruthwar and Amol V. Janorkar, Elastin-based Scaffolds for Local Delivery of Antibiotics and Proteins, Journal of Controlled Release (submitted), December 2011
- Shruti S. Amruthwar and Amol V. Janorkar, Collagen-Elastin like Polypeptide Composite Hydrogels for Model Drug and Protein Molecules Delivery,Journal of Biomaterials (submitted), January 2012
- Shruti S. Amruthwar and Amol V. Janorkar, Collagen-Elastin like Polypeptide Composite Scaffoldfor Effective Osteoblast Proliferation and Differentiation, Journal of Dental Research (submitted), January 2012