Bioinformatician Resume Boston MA - Hire IT People

Objective To secure a full time position in Bioinformatics .

Education
Masters of Science in Bioinformatics
Recipient of Graduate Student scholarship
Masters of Science in Genetics
Bachelors of Science in Microbiology, Genetics, Chemistry
Recipient of scholarship

Computer Skills
Operating System: Windows XP, Windows Vista, Mac, Linux, Unix
Specialities: Next Generation Sequencing, PLINK,KING, dbSNP, HapMap, UCSC genome browser, Circos visualization tool, NCBI, Pubmed, Genomic data formats like VCF, GVF, BED,etc.
DBMS,MS Office Suite, Perl, BioPerl, Java, PostgreSQL, MySQL, HTML, XML, Geneious, MATLAB,

Project
Pathway Analysis of P.aeruginosa in Cystic Fibrosis Patients
Worked in Prof. Kim Lewis‘s lab AntiMicrobial Discovery Centre at Northeastern University. Researched various data visualization tools. Utilized kegg tools and Prodonet 9.12 to obtain the list of metabolic pathways for the high persister mutants from eight different CF patients. Drawn comparisons to analyze the SNPs that are involved in the same metabolic subpathway in the overall pathway.Studied gene-gene interactions in Prodonet and found that GlyA1, GcvT2, GuaB, PA0065, PurF, PykA were essentially contributing to this disorder.

Work Experience

Confidential Boston,MA
Bioinformatician Feb2012-Present

Displayed Copy Number Variation data ploidy type ,ploidy score and CNV scores plots for four different CNV data files(data summarized on Complete Genomics platform) utilizing Circos genome visualization tool.
Developed a Perl converter to convert GVF to VCF format for the individual hg19 chromosome fasta files downloaded from the UCSC genome browser .
Developed a Perl converter to convert GVF file format to VCF format for the hg19 whole genome as a reference.
Developed a Perl parser to split a large VCF file having autism data for 411 individuals to smaller VCF files for each of these individuals. Used Annovar to analyze these files.

Confidential Boston, MA
Bioinformatics Research Co-op Summer 2011

Researched on how bad are the consequences of missense variations in causing disease. Obtained Condel scores from Ensembl variation database for a list of variants.
Accomplished analysis of whole genome utilizing PLINK for Identity by descent and Inbreeding coefficients writing Perl scripts.
Accomplished GWAS using King tool for getting kinship scores. Drawn comparison between PLINK and King tools and found that the King tool is more efficient.
Wrote Perl script to obtain the list of genes that are least probable in different types of statistical tests performed for updating company’s tools.
Wrote Perl script to obtain Phastcons scores for a list of variants matching with those in the UCSC genome browser.Wrote Perl script to get the variant sites overlapping with the allele coordinates of miRNA’s downloaded from miRBase database .
Wrote Perl script to parse out the number of drug responders and non responders with one or two variants for each gene in a sorted list of genes with different patterns of variants for 25 responders and 25 non responders respectively.
Automated Pubmed searches by writing a Perl script.
Developed Circos genome data visualization tool for Cancer utilizing JavaFX in Netbeans IDE. Also, queried company’s internal database to obtain 1000 Genomes genotypes using Perl.

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